dc.contributor.advisor | De la Cruz Flores, Mario Javier | |
dc.contributor.advisor | Sotero Solís, Víctor Erasmo | |
dc.contributor.author | Del Aguila Acosta, Christian Smith | |
dc.date.accessioned | 2024-05-28T18:13:50Z | |
dc.date.available | 2024-05-28T18:13:50Z | |
dc.date.issued | 2024 | |
dc.identifier.other | 615.952 D53 2024 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12737/10157 | |
dc.description.abstract | Objective: to determine the acute toxicity of the alcoholic and hydroalcoholic extract of leaves and stem of Senna occidentalis in nauplii of Artemia franciscana. Methodology: The Artemia eggs were acquired at the Fishmen Aquarium, located in the city of Iquitos, Department of Loreto. These eggs went through a hatching process until they became nauplii. A. franciscana eggs were incubated in a 3% Instant Ocean solution for 48 to 72 hours. For convenience, organs were collected from the study species and used to prepare both extracts from the micropulverized plant sample; The sample was macerated with ethanol, ethanol:water, then filtered, concentrated in rotary steam and subsequent physical elimination of the solvent, being tested at 10, 100 and 1000 ppm on A. franciscana nauplii. Results: The LC50 of the two extracts studied (alcoholic and hydroalcoholic) were higher than 1000 ppm. Conclusion: None of the extracts exhibited acute toxicity. | en_US |
dc.description.abstract | Objetivo: determinar la toxicidad aguda del extracto alcohólico e hidroalcohólico de hojas y tallo de Senna occidentalis en nauplios de Artemia franciscana. Metodología: Los huevos de Artemia fueron adquiridos en el Acuario Fishmen, ubicado en la ciudad de Iquitos, Departamento de Loreto. Estos huevos pasaron por un proceso de eclosión hasta convertirse en nauplios. los huevos de A. franciscana fueron incubados en una solución Instant Ocean al 3% durante 48 a 72 horas. Por conveniencia, se recolectaron órganos de las especies de estudio y se utilizaron para preparar ambos extractos a partir de la muestra vegetal micropulverizada; la muestra se maceró con etanol, etanol:agua, luego se filtró, se concentró en rota vapor y posterior eliminación física del solvente, siendo probados a 10, 100 y 1000 ppm sobre nauplios de A. franciscana. Resultados: La CL50 de los dos extractos estudiados (alcohólico e hidroalcohólico) fueron superior a 1000 ppm. Conclusión: Ninguno de los extractos exhibe toxicidad aguda. | es_PE |
dc.format | application/pdf | es_PE |
dc.language.iso | spa | es_PE |
dc.publisher | Universidad Nacional de la Amazonía Peruana | es_PE |
dc.rights | info:eu-repo/semantics/openAccess | * |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | * |
dc.subject | Toxicidad aguda | es_PE |
dc.subject | Extractos vegetales | es_PE |
dc.subject | Retamilla | es_PE |
dc.subject | Senna occidentalis | es_PE |
dc.subject | Nauplio (larva) | es_PE |
dc.subject | Artemia franciscana | es_PE |
dc.title | Toxicidad aguda del extracto alcohólico e hidroalcohólico de hojas y tallo de Senna occidentalis en nauplios de Artemia franciscana | es_PE |
dc.type | info:eu-repo/semantics/bachelorThesis | es_PE |
thesis.degree.discipline | Farmacia y Bioquímica | es_PE |
thesis.degree.grantor | Universidad Nacional de la Amazonía Peruana. Facultad de Farmacia y Bioquímica | es_PE |
thesis.degree.name | Químico(a) Farmacéutico(a) | es_PE |
dc.subject.ocde | https://purl.org/pe-repo/ocde/ford#3.01.05 | es_PE |
dc.subject.ocde | https://purl.org/pe-repo/ocde/ford#1.06.03 | es_PE |
renati.author.dni | 71024023 | |
renati.advisor.orcid | https://orcid.org/0000-0003-2212-3936 | |
renati.advisor.orcid | https://orcid.org/0000-0002-3562-605X | |
renati.advisor.dni | 40553043 | |
renati.advisor.dni | 05236521 | |
renati.type | https://purl.org/pe-repo/renati/type#tesis | es_PE |
renati.discipline | 917046 | es_PE |
renati.level | https://purl.org/pe-repo/renati/level#tituloProfesional | es_PE |
renati.juror | Nonato Ramirez, Luis Domingo | |
renati.juror | Jara Herrera, Cleto | |
renati.juror | Apagüeño Arévalo, Claudio Adriano | |
dc.publisher.country | PE | es_PE |